Two sample MR report


NAGK_Conventional Dendritic Cell against bbj-a-88

Date: 13 January, 2026


Results from two sample MR:

method nsnp b se pval
MR Egger 4 -0.1846003 0.2559346 0.5456587
Weighted median 4 -0.0478285 0.0192863 0.0131412
Inverse variance weighted 4 -0.0409793 0.0157996 0.0094950
Simple mode 4 -0.0514407 0.0277803 0.1611530
Weighted mode 4 -0.0503579 0.0257348 0.1453051

Heterogeneity tests

method Q Q_df Q_pval
MR Egger 2.243446 2 0.3257181
Inverse variance weighted 2.598198 3 0.4578056

Test for directional horizontal pleiotropy

egger_intercept se pval
0.0832393 0.1480162 0.6304901

Test that the exposure is upstream of the outcome

snp_r2.exposure snp_r2.outcome correct_causal_direction steiger_pval
8e-05 0 TRUE 0.3971604

Note - R^2 values are approximate


Forest plot of single SNP MR

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Comparison of results using different MR methods

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Funnel plot

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Leave-one-out sensitivity analysis

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